61
Fortin M, Dionne J, Pinho G, Gignac J, Almirall J, Lapointe L. Randomized controlled trials: do they have external validity for patients with multiple comorbidities? The Annals of Family Medicine. 2006;4(2):104.
Theory /Hypothesis
Groups
Patients
Evidence based practice
Study showing that the results of carefully controlled randomized trials do not easily translate in implementation in general practice because of frequent comorbidities that would have caused them to be excluded from the relevant trials
380